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Cheap Flights from Santo Domingo to Santiago de Cuba - Compare and Book on Opodo

Distance: 645 kms
Santo Domingo airports
Santiago de Cuba airports

Get the Best Deals on Flights from Santo Domingo to Santiago de Cuba

Discover the best last-minute airfares and cheap prices from Santo Domingo to Santiago de Cuba with Opodo Australia. Avoid overspending on flight tickets and start planning your perfect getaway. Opodo offers a hassle-free booking experience, providing access to top airline carriers and the most competitive prices.


Find the best flights that fit your needs

When do you want to depart from Santo Domingo? Adjust your travel dates and explore a wide range of options to Santiago de Cuba. With Opodo, you can find the perfect flight from our extensive selection, ensuring a seamless and enjoyable trip. Compare prices, flight durations, and amenities to choose the best option that suits your needs.


Book all in one place

But wait, there's more! Enhance your travel experience by booking a hotel and renting a car along with your flight. It's easier and often cheaper to book everything together. Choose the best offer from Santo Domingo to Santiago de Cuba and get ready for an incredible journey. Enjoy your holiday, and remember to fasten your seatbelt. We’re ready for takeoff!

Frequently asked questions about flights from Santo Domingo to Santiago de Cuba

How long does the flight take to go from Santo Domingo to Santiago de Cuba?
The total flight time between Santo Domingo and Santiago de Cuba is of around 01:40 hours on average, considering an average distance of 673 km, for both direct and indirect flights for the route (which may have 1 or more stops in other cities in between).
How can I find cheap flights from Santo Domingo to Santiago de Cuba at Opodo?
At Opodo we use different machine learned based methodologies to find our costumers the cheapest flight available from Santo Domingo to Santiago de Cuba. Considering airline combinations, stopovers and direct flights as well as different criteria for inbound and outbound journeys, our search engine works to provides always the best price with the best conditions.
Is it possible to purchase a flexible ticket for my flight from Santo Domingo to Santiago de Cuba?
At Opodo we want to make sure that your travel plans are not affected by any cancelation as well as any possible restrictions Cuba may apply when travelling from Santo Domingo. Is your flight cancelled? We've got your back! With our flexible ticket guarantee you can decide if you want to book another flight - free of rebooking fee - or get a full refund!
How is the weather in Santiago de Cuba compared to Santo Domingo?
While in Santo Domingo the temperatures can reach an average of 33.51 ºC in summer, with precipitation levels up to 12.0 mm ,Santiago de Cuba's temperatures can go up to 34.03 ºC during the hot season, with 6.0 mm average of rain rate . In winter, however, weather indicators show around 18.06 ºC in Santiago de Cuba, compared to the 16.48 ºC average degrees reported in Santo Domingo. During the winter period, Santo Domingo can register 12.0 mm precipitation, while Santiago de Cuba have an average of 3.0 mm rain level.
Which airports have flights between Santo Domingo and Santiago de Cuba?
The main airport route flying between Santo Domingo and Santiago de Cuba is: Las Americas (SDQ) to Antonio Maceo (SCU). This route is covered by the following airline(s): Cubana De Aviacion. InterCaribbean Airways.

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